Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Fate determination of adult human glial progenitor cells

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA156933 | ENA |

REPOSITORIES: ENA

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Publications

Fate determination of adult human glial progenitor cells.

Sim Fraser J FJ   Windrem Martha S MS   Goldman Steven A SA  

Neuron glia biology 20091007 3-4


Glial progenitor cells (GPCs) comprise the most abundant population of progenitor cells in the adult human brain. They are responsible for central nervous system (CNS) remyelination, and likely contribute to the astrogliotic response to brain injury and degeneration as well. Adult human GPCs are biased to differentiate as oligodendrocytes and elaborate new myelin, and yet they retain multilineage plasticity, and can give rise to neurons as well as astrocytes and oligodendrocytes once removed fro  ...[more]

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