Project description:We used small RNA-Seq to characterize heart non-coding RNAs in 85 inbred strains of mice from the Hybrid Mouse Diversity Panel (HMDP), a reference resource population for cardiovascular and metabolic traits.
Project description:Identify genes in the heart whose expressions under genetic regulation in the hybrid mouse diversity panel. The hybrid mouse diversity panel is comprised of classical inbred and recombinant inbred wild type mice. The RMA values of genes were used for genome wide association as described in Bennett et al Genome Research 2010. These data used to identify candidate genes at loci associated with atherosclerosis.