Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: DDR1 knockdown in BXPC3 cell line

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA170202 | ENA |

REPOSITORIES: ENA

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Publications


Discoidin domain receptor 1 (DDR1) is a member of the receptor tyrosine kinase family. The receptor is activated upon binding to its ligand, collagen, and plays a crucial role in many fundamental processes such as cell differentiation, adhesion, migration and invasion. Although DDR1 is expressed in many normal tissues, upregulated expression of DDR1 in a variety of human cancers such as lung, colon and brain cancers is known to be associated with poor prognosis. Using shRNA silencing, we assesse  ...[more]

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