Genomics

Dataset Information

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ABSTRACT: DNA Methylation Changes and Childhood Asthma in the Inner City

PROVIDER: PRJNA174783 | ENA |

REPOSITORIES: ENA

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Epigenetic marks are heritable, influenced by the environment, direct the maturation of T lymphocytes, and in mice enhance the development of allergic airway disease. Thus it is important to define epigenetic alterations in asthmatic populations.We hypothesize that epigenetic alterations in circulating PBMCs are associated with allergic asthma.We compared DNA methylation patterns and gene expression in inner-city children with persistent atopic asthma versus healthy control subjects by using DNA  ...[more]

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