Project description:Expression profiles of microRNAs in neonatal (isolated from day0 newborn rats) and adult rat cardiomyocytes (isolated from 2month old rats) Two condition experiment; Biological replicates: 7 samples of cardiomyocytes from neonatal rats (from independent isolations); 6 samples of cardiomyocytes isolated from adult animals (from independent isolations)

2012-10-13 | E-GEOD-41537 | biostudies-arrayexpress

Comparison of neonatal and adult rat ventricular cardiomyocytes

Project description:We addressed the question of which protein kinases are expressed in cardiomyocytes. We assessed the changes during postnatal development, comparing profiles in rat neonatal ventricular cardiomyocytes (NVMs) with adult ventricular cardiomyocytes (AVMs). Neonatal and adult rat ventricular cardiomyocytes prepared according to established procedures (Marshall et al. PLoS ONE 2010 5(4):e10027; Fuller and Sugden, FEBs Lett. 1989 247:209-12; Rodrigues and Severson In Biochemical Techniques in the Heart (McNeill, J. H., Ed.) pp 101-115, CRC Press, New York.). mRNA expression profiles compared using Affymetrix rat genome 230 2.0 arrays.

2015-01-01 | E-MTAB-2832 | biostudies-arrayexpress

JMJD4 regulates PKM2 degradation of cardiomyocytes and is critical in the development of dilated cardiomyopathy

Project description:RNA-Seq results of adult mouse cardiomyocytes with Jmjd4 knockout and neonatal rat cardiomyocytes with Jmjd4 knockdown. To investigate the role of Jmjd4 in dilated cardiomyopathy, we performed gene expression profiling with RNA-Seq results from heart samples of MCM+ Jmjd4f/f and control Jmjd4f/f mice, as well as neonatal rat ventricuar cardiomyocytes (NRVCs) treated with si-Jmjd4 and si-NC control.

2022-08-30 | GSE211955 | GEO

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