Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: DNA repair genes: Alternative transcription and gene expression at the exon level in response to the DNA damaging agent, ionizing radiation

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA178300 | ENA |

REPOSITORIES: ENA

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Publications

DNA repair genes: alternative transcription and gene expression at the exon level in response to the DNA damaging agent, ionizing radiation.

Forrester Helen B HB   Li Jason J   Hovan Daniel D   Ivashkevich Alesia N AN   Sprung Carl N CN  

PloS one 20121228 12


DNA repair is an essential cellular process required to maintain genomic stability. Every cell is subjected to thousands of DNA lesions daily under normal physiological conditions. Ionizing radiation (IR) is a major DNA damaging agent that can be produced by both natural and man-made sources. A common source of radiation exposure is through its use in medical diagnostics or treatments such as for cancer radiotherapy where relatively high doses are received by patients. To understand the detailed  ...[more]

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