Dataset Information


Mus musculus

ABSTRACT: Gene expression data from differentiated 3T3-L1 preadipocytes treated with Palmitic Acid, Stearic Acid, Palmitoleic Acid, or Oleic Acid

ORGANISM(S): Mus musculus  



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Individual saturated and monounsaturated fatty acids trigger distinct transcriptional networks in differentiated 3T3-L1 preadipocytes.

Shaw Brittany B   Lambert Samuel S   Wong Monica H T MH   Ralston Jessica C JC   Stryjecki Carolina C   Mutch David M DM  

Journal of nutrigenetics and nutrigenomics 20130206 1

BACKGROUND/AIMS: Saturated fatty acids (SFA) are widely thought to induce inflammation in adipose tissue (AT), while monounsaturated fatty acids (MUFA) are purported to have the opposite effect; however, it is unclear if individual SFA and MUFA behave similarly. Our goal was to examine adipocyte transcriptional networks regulated by individual SFA (palmitic acid, PA; stearic acid, SA) and MUFA (palmitoleic acid, PMA; oleic acid, OA). METHODS: Differentiated preadipocytes were treated with either  ...[more]

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