Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: GeneChip Mapping 500K set and Genome-Wide Human SNP 6.0 Array for glioblastomas

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA182381 | ENA |

REPOSITORIES: ENA

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Publications

Detailed characterization of alterations of chromosomes 7, 9, and 10 in glioblastomas as assessed by single-nucleotide polymorphism arrays.

Crespo Inês I   Vital Ana Luísa AL   Nieto Ana Belen AB   Rebelo Olinda O   Tão Hermínio H   Lopes Maria Celeste MC   Oliveira Catarina Resende CR   French Pim J PJ   Orfao Alberto A   Tabernero María Dolores MD  

The Journal of molecular diagnostics : JMD 20110830 6


Glioblastomas are cytogenetically heterogeneous tumors that frequently display alterations of chromosomes 7, 9p, and 10q. We used high-density (500K) single-nucleotide polymorphism arrays to investigate genome-wide copy number alterations and loss of heterozygosity in 35 primary glioblastomas. We focused on the identification and detailed characterization of alterations involving the most frequently altered chromosomes (chromosomes 7, 9, and 10), the identification of distinct prognostic subgrou  ...[more]

Publication: 1/2

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