Dataset Information


Mus musculus

ABSTRACT: Effects of overexpressed Atoh8 on the transcriptional profile of mouse ductal cells mPAC in the absence or presence of co-expressed Neurogenin3

ORGANISM(S): Mus musculus  



altmetric image


Characterization of the transcriptional activity of the basic helix-loop-helix (bHLH) transcription factor Atoh8.

Ejarque Miriam M   Altirriba Jordi J   Gomis Ramon R   Gasa Rosa R  

Biochimica et biophysica acta 20130809 11

The atonal-related Neurogenin/NeuroD family of basic helix-loop-helix (bHLH) transcription factors comprises potent inducers of neuronal and endocrine differentiation programs in the nervous and digestive system. Atonal homolog 8 (Atoh8) displays high similarity in the bHLH domain with NeuroD proteins. Yet, available evidences indicate that Atoh8 has distinctive features including a ubiquitous expression pattern in embryonic tissues and the ability to inhibit differentiation. To gain insights in  ...[more]

Similar Datasets

| PRJNA392281 | ENA
| GSE86988 | GEO
| GSE63526 | GEO
2015-11-20 | E-GEOD-63526 | ArrayExpress
2012-07-09 | E-GEOD-39205 | ArrayExpress
2010-07-30 | GSE23308 | GEO
2010-07-30 | E-GEOD-23308 | ArrayExpress
| GSE63348 | GEO
2012-02-20 | E-GEOD-34801 | ArrayExpress
| PRJNA278114 | ENA