Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Microarray to find ATF5 dependent genes in response to proteasome inhibition

OTHER RELATED OMICS DATASETS IN: E-GEOD-43714E-GEOD-43713

PROVIDER: PRJNA187149 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Mus musculus

Project description:Microarray to find CHOP dependent genes in response to proteasome inhibition

| PRJNA187148 | ENA

Project description:Microarray to find CHOP/ATF5 dependent genes in response to proteasome inhibition

| PRJNA187146 | ENA

E-GEOD-43714

Project description:Microarray to find ATF5 dependent genes in response to proteasome inhibition

2015-07-10 | E-GEOD-43714 | ExpressionAtlas

E-GEOD-43713

Project description:Microarray to find CHOP dependent genes in response to proteasome inhibition

2015-07-10 | E-GEOD-43713 | ExpressionAtlas

Mus musculus

Project description:Cellular response to proteasome inhibition by Bortezomib

| PRJNA290443 | ENA

Bidirectional Introgression between Mus musculus domesticus and Mus spretus.

Project description: Not available

| S-EPMC8784167 | biostudies-literature

Testis expression in Mus musculus domesticus WSB/EiJ x Mus musculus musculus PWD/PhJ F2 hybrids

Project description:To characterize the genetic basis of hybrid male sterility in detail, we used a systems genetics approach, integrating mapping of gene expression traits with sterility phenotypes and QTL. We measured genome-wide testis expression in 305 male F2s from a cross between wild-derived inbred strains of M. musculus musculus and M. m. domesticus. We identified several thousand cis- and trans-acting QTL contributing to expression variation (eQTL). Many trans eQTL cluster into eleven ‘hotspots,’ seven of which co-localize with QTL for sterility phenotypes identified in the cross. The number and clustering of trans eQTL - but not cis eQTL - were substantially lower when mapping was restricted to a ‘fertile’ subset of mice, providing evidence that trans eQTL hotspots are related to sterility. Functional annotation of transcripts with eQTL provides insights into the biological processes disrupted by sterility loci and guides prioritization of candidate genes. Using a conditional mapping approach, we identified eQTL dependent on interactions between loci, revealing a complex system of epistasis. Our results illuminate established patterns, including the role of the X chromosome in hybrid sterility.

2014-05-01 | GSE54089 | GEO

Long terminal repeat retrotransposons of Mus musculus.

Project description: Not available

| S-EPMC395764 | biostudies-literature

Genomic copy number variation in Mus musculus.

Project description: Not available

| S-EPMC4490682 | biostudies-literature

Sex-dependent modulation of ultrasonic vocalizations in house mice (Mus musculus musculus).

Project description: Not available

| S-EPMC5728457 | biostudies-literature