Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Expression profiling of glioma initiating cells (GICs) in the sphere and differentiation conditions

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA187361 | ENA |

REPOSITORIES: ENA

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Publications


Glioma initiating cells (GICs) are considered responsible for the therapeutic resistance and recurrence of malignant glioma. To clarify the molecular mechanism of GIC maintenance/differentiation, we established GIC clones having the potential to differentiate into malignant gliomas, and subjected to DNA microarray/iTRAQ based integrated proteomics. 21,857 mRNAs and 8,471 proteins were identified and integrated into a gene/protein expression analysis chart. Gene Ontology analysis revealed that th  ...[more]

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