Genomics

Dataset Information

0

Drosophila melanogaster


ABSTRACT: High-resolution mapping defines the cooperative architecture of Polycomb Response Elements

ORGANISM(S): Drosophila melanogaster  

PROVIDER: PRJNA208052 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR1056274_1.fastq.gz Fastqsanger.gz
SRR1056274_2.fastq.gz Fastqsanger.gz
SRR1056275_1.fastq.gz Fastqsanger.gz
SRR1056275_2.fastq.gz Fastqsanger.gz
SRR1056276_1.fastq.gz Fastqsanger.gz
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Publications

High-resolution mapping defines the cooperative architecture of Polycomb response elements.

Orsi Guillermo A GA   Kasinathan Sivakanthan S   Hughes Kelly T KT   Saminadin-Peter Sarah S   Henikoff Steven S   Ahmad Kami K  

Genome research 20140325 5


Polycomb-mediated chromatin repression modulates gene expression during development in metazoans. Binding of multiple sequence-specific factors at discrete Polycomb response elements (PREs) is thought to recruit repressive complexes that spread across an extended chromatin domain. To dissect the structure of PREs, we applied high-resolution mapping of nonhistone chromatin proteins in native chromatin of Drosophila cells. Analysis of occupied sites reveal interactions between transcription factor  ...[more]

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