Dataset Information


Gallus gallus

ABSTRACT: Neuropeptides:developmental signals in placode progenitor formation

ORGANISM(S): Gallus gallus  



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Cell interactions, signals and transcriptional hierarchy governing placode progenitor induction.

Hintze Mark M   Prajapati Ravindra Singh RS   Tambalo Monica M   Christophorou Nicolas A D NAD   Anwar Maryam M   Grocott Timothy T   Streit Andrea A  

Development (Cambridge, England) 20170706 15

In vertebrates, cranial placodes contribute to all sense organs and sensory ganglia and arise from a common pool of Six1/Eya2+ progenitors. Here we dissect the events that specify ectodermal cells as placode progenitors using newly identified genes upstream of the Six/Eya complex. We show in chick that two different tissues, namely the lateral head mesoderm and the prechordal mesendoderm, gradually induce placode progenitors: cells pass through successive transcriptional states, each identified  ...[more]

Publication: 1/2

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