Project description:Circadian input kinas A (cikA) null cells severly distorts the genome-wide output of the circadian clock Synechococcus cultures (both wildtype and M-NM-^TcikA null cells) were synchronized with two light-dark (12h:12h) cycle before release into continuous light. Samples were collected at 4 h intervals for the next 24 h, total RNA was isolated from samples collected at each time points and genome-wide expression was measured using custom-designed microarrays