Genomics

Dataset Information

118

Mus musculus


ABSTRACT: Single-cell RNA-seq reveals dynamic paracrine control of cellular variation

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA212439 | ENA |

REPOSITORIES: ENA

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Publications


High-throughput single-cell transcriptomics offers an unbiased approach for understanding the extent, basis and function of gene expression variation between seemingly identical cells. Here we sequence single-cell RNA-seq libraries prepared from over 1,700 primary mouse bone-marrow-derived dendritic cells spanning several experimental conditions. We find substantial variation between identically stimulated dendritic cells, in both the fraction of cells detectably expressing a given messenger RNA  ...[more]

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