Project description:We performed a transcriptome analysis of Ruminococcus gnavus with and without 0.1% (w/w) agarooligosaccharide exposure to validate the mechanism of growth inhibition.
Project description:Strain Ruminococcus gnavus TSDC16.1-2.1 (species Ruminococcus gnavus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.
Project description:Strain Ruminococcus gnavus TSDC16.1-1.1 (species Ruminococcus gnavus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.
Project description:Strain Ruminococcus gnavus TSDC16.1-3.1 (species Ruminococcus gnavus) was isolated from the fecal microbiota of a USA female at time point zero . The species name was assigned by genome clustering.
Project description:Lacticaseibacillus rhamnosus GG (LGG) is a widely consumed probiotic whose potential beneficial effects in humans have been examined in over 250 clinical trials. However, the mechanisms by which LGG modulates host gut physiology remains unknown. R. gnavus is a pathobiont that is strongly associated with inflammatory bowel diseases. Germ free mice were mono-associated with L. rhamonosus (LGG) or R. gnavus (RG) for 21 days, ileum bulk RNA-seq were performed to compare the transcriptomic profiles of LGG or RG associated mice with the transcriptome of germ-free mouse ileum.
