Project description:SPO11-promoted DNA double-strand breaks (DSBs) formation is a crucial step for meiotic recombination, and it is indispensable to detect the broken DNA ends accurately for dissecting the molecular mechanisms behind. Here, we report a novel technique, named DEtail-seq (DNA End tailing followed by sequencing), that can directly and quantitatively capture the meiotic DSB 3’ overhang hotspots at single-nucleotide resolution.

2023-01-08 | GSE154226 | GEO

Saccharomyces cerevisiae

Project description:Spo11-accessory proteins link DNA double-strand break sites to the chromosome axis in early meiotic recombination

| PRJNA140909 | ENA

Saccharomyces cerevisiae S288c x YJM789

Project description:Down-regulation of Rad51 Activity During Meiosis in Yeast Prevents Competition with Dmc1 for Repair of Double-Strand Breaks

| PRJNA217886 | ENA

Saccharomyces cerevisiae YJM789

Project description:The sequencing of Saccharomyces cerevisiae strains.

| PRJNA215584 | ENA

Saccharomyces cerevisiae YJM789

Project description:WGS sequencing and assembly