Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Induction of Ground-State Pluripotency by Minimal Factor Episomal-Expression in Single Cell Format

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA219202 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

Platform for induction and maintenance of transgene-free hiPSCs resembling ground state pluripotent stem cells.

Valamehr Bahram B   Robinson Megan M   Abujarour Ramzey R   Rezner Betsy B   Vranceanu Florin F   Le Thuy T   Medcalf Amanda A   Lee Tom Tong TT   Fitch Michael M   Robbins David D   Flynn Peter P  

Stem cell reports 20140306 3


Cell banking, disease modeling, and cell therapy applications have placed increasing demands on hiPSC technology. Specifically, the high-throughput derivation of footprint-free hiPSCs and their expansion in systems that allow scaled production remains technically challenging. Here, we describe a platform for the rapid, parallel generation, selection, and expansion of hiPSCs using small molecule pathway inhibitors in stage-specific media compositions. The platform supported efficient and expedite  ...[more]

Similar Datasets

2018-11-07 | PXD009217 | Pride
2014-06-04 | E-MTAB-2366 | ArrayExpress
2014-06-04 | E-MTAB-2365 | ArrayExpress
| GSE92273 | GEO
2015-12-07 | E-MTAB-4068 | ArrayExpress
2013-10-21 | E-GEOD-43682 | ArrayExpress
2011-10-03 | E-GEOD-32581 | ArrayExpress
2011-10-04 | GSE32581 | GEO
| PRJNA259876 | ENA
2017-02-22 | PXD005581 | Pride