Dataset Information


Homo sapiens

ABSTRACT: Expression profiling identifies deregulated pathways and top diagnostic markers in papillary thyroid carcinoma

ORGANISM(S): Homo sapiens  



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High Diagnostic Accuracy Based on CLDN10, HMGA2, and LAMB3 Transcripts in Papillary Thyroid Carcinoma.

Barros-Filho Mateus Camargo MC   Marchi Fabio Albuquerque FA   Pinto Clóvis Antônio CA   Rogatto Silvia Regina SR   Kowalski Luiz Paulo LP  

The Journal of clinical endocrinology and metabolism 20150413 6

CONTEXT:Thyroid nodules are common in adult population and papillary thyroid carcinoma (PTC) is the most frequent malignant finding. The natural history of PTC remains poorly understood and current diagnostic methods limitations are responsible for a significant number of potentially avoidable surgeries. OBJECTIVE:This study aimed to identify molecular markers to improve the diagnosis of thyroid lesions. DESIGN:Gene expression profiling was performed using microarray in 61 PTC and 13 surrounding  ...[more]

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