Genomics

Dataset Information

118

A species-specific nucleosomal signature defines a periodic distribution of amino acids in proteins


ABSTRACT: A species-specific nucleosomal signature defines a periodic distribution of amino acids in proteins

PROVIDER: PRJNA227083 | ENA |

REPOSITORIES: ENA

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A species-specific nucleosomal signature defines a periodic distribution of amino acids in proteins.

Quintales Luis L   Soriano Ignacio I   Vázquez Enrique E   Segurado Mónica M   Antequera Francisco F  

Open biology 20150401 4


Nucleosomes are the basic structural units of chromatin. Most of the yeast genome is organized in a pattern of positioned nucleosomes that is stably maintained under a wide range of physiological conditions. In this work, we have searched for sequence determinants associated with positioned nucleosomes in four species of fission and budding yeasts. We show that mononucleosomal DNA follows a highly structured base composition pattern, which differs among species despite the high degree of histone  ...[more]

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