Project description:Differential gene expression was determined between wild type Streptococcus mutan and a yidC1 or yidC2 mutant using whole transcriptome RNA sequence. A significantly greater number of genes were differentially expressed (DE) in the yidC2 mutant (320 DE genes) compared to wildtype, while the yidC1 mutant had only 21 DE genes when compared to wildtype.
Project description:Transcriptional profiling of S. mutans cells comparing WT cells with lytS cells at early- and late-exponential growth phase. Four-condition experiment, WT vs. lytS cells and optical density (600nm) 0.2 vs. 0.9. Biological replicates: 4 wild-type, 4 lytS mutant, independently grown and harvested. One replicate per array.
