Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA229561 | ENA |

REPOSITORIES: ENA

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Publications

Nuclear receptor-mediated alleviation of alcoholic fatty liver by polyphenols contained in alcoholic beverages.

Yao Ruiqing R   Yasuoka Akihito A   Kamei Asuka A   Ushiama Shota S   Kitagawa Yoshinori Y   Rogi Tomohiro T   Shibata Hiroshi H   Abe Keiko K   Misaka Takumi T  

PloS one 20140203 2


To elucidate the effect of the polyphenols contained in alcoholic beverages on the metabolic stress induced by ethanol consumption, four groups of mice were fed for five weeks on Lieber's diet with or without ethanol, with ethanol plus ellagic acid, and with ethanol plus trans-resveratrol. Alcoholic fatty liver was observed in the group fed the ethanol diet but not in those fed the ethanol plus polyphenol diets. Liver transcriptome analysis revealed that the addition of the polyphenols suppresse  ...[more]

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