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Mus musculus

ABSTRACT: Identification of Sox3 targets in mouse neural progenitor cells

OTHER RELATED OMICS DATASETS IN: E-GEOD-53760

PROVIDER: PRJNA232818 | ENA |

REPOSITORIES: ENA

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Identification of Sox3 targets in mouse neural progenitor cells

2014-02-28 | GSE53760 | GEO

Identification of Sox3 targets in mouse neural progenitor cells

Project description:Sox3 has been shown to be expressed within neural progenitors of the developing mouse central nervous system. However, identification of Sox3 targets within neural progenitors has remained elusive. Using microarrays we compared populations of in vitro derived mouse neural progenitor cells, with or without Sox3, to identify putative Sox3 neural progenitor targets. Mouse R1 ES cells, with or without Sox3, were differentiated into neural progenitor cells using the standard N2B27 protocols. At the fourth day of N2B27 differentiation, over two independent series, RNA was extracted from both Sox3 positive and Sox3 null populations and hybridization on a GeneChip Mouse Gene 1.0 ST Affymetrix microarrays.

2014-02-28 | E-GEOD-53760 | biostudies-arrayexpress

E-GEOD-53760

Project description:Identification of Sox3 targets in mouse neural progenitor cells

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Identification of Highly Conserved Putative Developmental Enhancers Bound by SOX3 in Neural Progenitors Using ChIP-Seq

Project description:SOX3 is highly expressed in neural progenitor cells (NPC) within the developing mouse cetral nervous system. A ChIP-Seq experiement was performed for SOX3 in NPCs derived from embryonic stem cells. Identification of SOX3 binidng sites from 3 independent ChIP-seq samples in NPCs

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Identification of Highly Conserved Putative Developmental Enhancers Bound by SOX3 in Neural Progenitors Using ChIP-Seq

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