Project description:Illumina HiSeq2500 technology was used to generate mRNA profiles from Gymnopus androsaceus grown on pine needles for 2, 5 and 10 months. Paired-end reads of 125 bp were generated and aligned to Gymnopus androsaceus reference transcripts using CLC Genomics Workbench 9.
Project description:Primary objectives: The primary objective is to investigate circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).
Primary endpoints: circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).
