Dataset Information


Mus musculus

ABSTRACT: Histone H3 Acetylation and microRNA(s) Regulate Inflammatory response in Mastitis Mice, induced by Staphylococcus aureus Infection [Microarray]

ORGANISM(S): Mus musculus  



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Epigenetic response in mice mastitis: Role of histone H3 acetylation and microRNA(s) in the regulation of host inflammatory gene expression during Staphylococcus aureus infection.

Modak Rahul R   Das Mitra Susweta S   Vasudevan Madavan M   Krishnamoorthy Paramanandhan P   Kumar Manoj M   Bhat Akshay V AV   Bhuvana Mani M   Ghosh Sankar K SK   Shome Bibek R BR   Kundu Tapas K TK  

Clinical epigenetics 20140630 1

There is renewed interest towards understanding the host-pathogen interaction in the light of epigenetic modifications. Although epithelial tissue is the major site for host-pathogen interactions, there is handful of studies to show how epithelial cells respond to pathogens. Bacterial infection in the mammary gland parenchyma induces local and subsequently systemic inflammation that results in a complex disease called mastitis. Globally Staphylococcus aureus is the single largest mastitis pathog  ...[more]

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