Genomics

Dataset Information

118

Homo sapiens


ABSTRACT: InFusion: advancing discovery of fusion genes and chimeric transcripts from RNA-seq data

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA243568 | ENA |

REPOSITORIES: ENA

altmetric image

Publications

InFusion: Advancing Discovery of Fusion Genes and Chimeric Transcripts from Deep RNA-Sequencing Data.

Okonechnikov Konstantin K   Imai-Matsushima Aki A   Paul Lukas L   Seitz Alexander A   Meyer Thomas F TF   Garcia-Alcalde Fernando F  

PloS one 20161201 12


Analysis of fusion transcripts has become increasingly important due to their link with cancer development. Since high-throughput sequencing approaches survey fusion events exhaustively, several computational methods for the detection of gene fusions from RNA-seq data have been developed. This kind of analysis, however, is complicated by native trans-splicing events, the splicing-induced complexity of the transcriptome and biases and artefacts introduced in experiments and data analysis. There a  ...[more]

Similar Datasets

| GSE56512 | GEO
2011-09-01 | E-GEOD-29098 | ArrayExpress
2013-12-06 | E-GEOD-51124 | ArrayExpress
2009-01-19 | GSE14435 | GEO
2010-05-06 | E-GEOD-14435 | ArrayExpress
| EGAS00001000659 | EGA
2010-12-31 | phs000310 | dbGaP
| PRJNA451407 | ENA
| phs001707 | dbGaP
2020-08-11 | PXD015231 | Pride