Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Expression profiling of tumor cells from MYCN-driven neuroblastoma upon BRD4 or AURKA inhibition

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA248139 | ENA |

REPOSITORIES: ENA

altmetric image

Publications


Neuroblastoma, a childhood cancer that originates from neural crest-derived cells, is the most common deadly solid tumor of infancy. Amplification of the MYCN oncogene, which occurs in approximately 20-25% of human neuroblastomas, is the most prominent genetic marker of high-stage disease. The availability of valid preclinical in vivo models is a prerequisite to develop novel targeted therapies. We here report on the generation of transgenic mice with Cre-conditional induction of MYCN in dopamin  ...[more]

Similar Datasets

2016-05-03 | E-MTAB-3672 | ExpressionAtlas
2016-07-03 | E-MTAB-3672 | ArrayExpress
| GSE72678 | GEO
2012-03-31 | E-GEOD-32386 | ArrayExpress
2014-05-19 | E-GEOD-16480 | ArrayExpress
| GSE16480 | GEO
| GSE71060 | GEO
| GSE71061 | GEO
| GSE71105 | GEO
| GSE71059 | GEO