Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Transcriptional profiling of PRDM2 Knock down vs.controlGFPsh differentiated C2C12 Myoblasts (D28hrs)

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA253138 | ENA |

REPOSITORIES: ENA

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Publications

Identification of PRDM2 regulated genes in quiescent C2C12 myoblasts.

Cheedipudi Sirisha S   Gala Hardik P HP   Puri Deepika D   Dhawan Jyotsna J  

Genomics data 20151023


Quiescent stem cells contribute to tissue homeostasis and repair in adult mammals. We identified a tumor suppressor PRDM2, as an epigenetic regulator induced in quiescent muscle stem cells as well as in cultured quiescent myoblasts. To delineate the functions of PRDM2 in muscle cells, we compared the gene expression profiles of control and PRDM2 knockdown myoblasts in growing, differentiating and quiescent conditions (GEO accession number: GSE 58676). To identify the direct targets of PRDM2 and  ...[more]

Publication: 1/2

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