Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Establishment of trophoblast stem cells under defined culture conditions in mice

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA254454 | ENA |

REPOSITORIES: ENA

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Publications

Establishment of trophoblast stem cells under defined culture conditions in mice.

Ohinata Yasuhide Y   Tsukiyama Tomoyuki T  

PloS one 20140909 9


The inner cell mass (ICM) and trophoblast cell lineages duet early embryonic development in mammals. After implantation, the ICM forms the embryo proper as well as some extraembryonic tissues, whereas the trophoectoderm (TE) exclusively forms the fetal portion of the placenta and the trophoblast giant cells. Although embryonic stem (ES) cells can be derived from ICM in cultures of mouse blastocysts in the presence of LIF and/or combinations of small-molecule chemical compounds, and the undiffere  ...[more]

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