Dataset Information


Homo sapiens

ABSTRACT: Different Preference of Degradome in Invasion versus Angiogenesis

ORGANISM(S): Homo sapiens  



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Different Preference of Degradome in Invasion versus Angiogenesis.

Ghaffari-Tabrizi-Wizsy Nassim N   Cvitic Silvija S   Tam-Amersdorfer Carmen C   Bilban Martin M   Majali-Martinez Alejandro A   Schramke Karin K   Desoye Gernot G   Hiden Ursula U  

Cells, tissues, organs 20140101 3-4

Proteases are required for a multitude of cellular processes including homeostatic tissue remodelling, invasion and angiogenesis. The physiological function of a cell or tissue is reflected by the set of proteases expressed, also termed degradome. The role of proteases in invasion and angiogenesis has been studied intensively, mostly in cancer. We aimed to compare the set of proteases required for physiological invasion versus physiological angiogenesis from cells deriving from the same organ, a  ...[more]

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