Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Transcriptional and epigenetic program changes of induced beta cells over time [expression array]

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA255422 | ENA |

REPOSITORIES: ENA

altmetric image

Publications


Direct lineage conversion is a promising approach to generate therapeutically important cell types for disease modeling and tissue repair. However, the survival and function of lineage-reprogrammed cells in vivo over the long term has not been examined. Here, using an improved method for in vivo conversion of adult mouse pancreatic acinar cells toward beta cells, we show that induced beta cells persist for up to 13 months (the length of the experiment), form pancreatic islet-like structures and  ...[more]

Similar Datasets

| PRJNA255762 | ENA
2011-07-14 | BIOMD0000000342 | BioModels
| EGAS00001000742 | EGA
| EGAD00001000828 | EGA
2010-02-19 | GSE20403 | GEO
2014-11-15 | E-GEOD-59615 | ArrayExpress
| GSE59490 | GEO
2016-07-22 | MSV000079979 | Massive
2011-01-19 | BIOMD0000000301 | BioModels
2005-01-01 | MODEL1204040000 | BioModels