Genomics

Dataset Information

294

Homo sapiens


ABSTRACT: Ribosome profiling and RNA sequencing of MCF10A cells treated with torin or by serum starvation

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA256320 | ENA |

REPOSITORIES: ENA

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Publications


Tumour growth and metabolic adaptation may restrict the availability of certain amino acids for protein synthesis. It has recently been shown that certain types of cancer cells depend on glycine, glutamine, leucine and serine metabolism to proliferate and survive. In addition, successful therapies using L-asparaginase-induced asparagine deprivation have been developed for acute lymphoblastic leukaemia. However, a tailored detection system for measuring restrictive amino acids in each tumour is c  ...[more]

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