Genomics,Multiomics

Dataset Information

0

Schizosaccharomyces pombe


ABSTRACT: Dicer and Hsp104 function in a negative feedback loop to confer epigenetic robustness [RNA_profiles]

OTHER RELATED OMICS DATASETS IN: E-GEOD-60640E-GEOD-60638E-GEOD-60429

PROVIDER: PRJNA258226 | ENA |

REPOSITORIES: ENA

Dataset's files

Source:
Action DRS
SRR1551870.fastq.gz Fastqsanger.gz
SRR1551868.fastq.gz Fastqsanger.gz
SRR1551869.fastq.gz Fastqsanger.gz
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Publications

Dicer and Hsp104 function in a negative feedback loop to confer robustness to environmental stress.

Oberti Daniele D   Biasini Adriano A   Kirschmann Moritz Alexander MA   Genoud Christel C   Stunnenberg Rieka R   Shimada Yukiko Y   Bühler Marc M  

Cell reports 20141224 1


Epigenetic mechanisms can be influenced by environmental cues and thus evoke phenotypic variation. This plasticity can be advantageous for adaptation but also detrimental if not tightly controlled. Although having attracted considerable interest, it remains largely unknown if and how environmental cues such as temperature trigger epigenetic alterations. Using fission yeast, we demonstrate that environmentally induced discontinuous phenotypic variation is buffered by a negative feedback loop that  ...[more]

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