Dataset Information


Bos taurus

ABSTRACT: DNA methylation profiles in the uterus during subclinical endometritis

ORGANISM(S): Bos taurus  



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Modulation of the immune system during postpartum uterine inflammation.

Walker Caroline G CG   Meier Susanne S   Hussein Hassan H   McDougall Scott S   Burke Chris R CR   Roche John R JR   Mitchell Murray D MD  

Physiological genomics 20150120 4

Postpartum uterine inflammation (endometritis) in the dairy cow is associated with lower fertility at both the time of infection and after the inflammation has resolved. We hypothesized that aberrant DNA methylation may be involved in the subfertility associated with uterine inflammation. The objective of this study was to characterize genome-wide DNA methylation and gene expression in the endometrium of dairy cows with subclinical endometritis (SCE). Endometrial tissues were obtained at 29 days  ...[more]

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