Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Epigenome analysis of fetal and adult liver samples

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA260642 | ENA |

REPOSITORIES: ENA

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Publications


BACKGROUND: The liver plays a central role in the maintenance of homeostasis and health in general. However, there is substantial inter-individual variation in hepatic gene expression, and although numerous genetic factors have been identified, less is known about the epigenetic factors. RESULTS: By analyzing the methylomes and transcriptomes of 14 fetal and 181 adult livers, we identified 657 differentially methylated genes with adult-specific expression, these genes were enriched for transcrip  ...[more]

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