Genomics

Dataset Information

118

Mus musculus


ABSTRACT: High throughput quantitative whole transcriptome analysis of CC10- B4+ and Krt5-CreERT2 - labeled distal lung cells

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA260708 | ENA |

REPOSITORIES: ENA

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Publications


Broadly, tissue regeneration is achieved in two ways: by proliferation of common differentiated cells and/or by deployment of specialized stem/progenitor cells. Which of these pathways applies is both organ- and injury-specific. Current models in the lung posit that epithelial repair can be attributed to cells expressing mature lineage markers. By contrast, here we define the regenerative role of previously uncharacterized, rare lineage-negative epithelial stem/progenitor (LNEP) cells present wi  ...[more]

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