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Homo sapiens

ABSTRACT: Expression Analysis of Human Adipose-Derived Stem Cells During In Vitro Differentiation to an Adipocyte Lineage



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Expression analysis of human adipose-derived stem cells during in vitro differentiation to an adipocyte lineage.

Satish Latha L   Krill-Burger J Michael JM   Gallo Phillip H PH   Etages Shelley Des SD   Liu Fang F   Philips Brian J BJ   Ravuri Sudheer S   Marra Kacey G KG   LaFramboise William A WA   Kathju Sandeep S   Rubin J Peter JP  

BMC medical genomics 20150724

<h4>Background</h4>Adipose tissue-derived stromal stem cells (ASCs) represent a promising regenerative resource for soft tissue reconstruction. Although autologous grafting of whole fat has long been practiced, a major clinical limitation of this technique is inconsistent long-term graft retention. To understand the changes in cell function during the transition of ASCs into fully mature fat cells, we compared the transcriptome profiles of cultured undifferentiated human primary ASCs under condi  ...[more]

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