Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Treatment of C3H/HeJ grafted mice with baricitinib [topical]

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA261450 | ENA |

REPOSITORIES: ENA

altmetric image

Publications


Alopecia areata (AA) is an autoimmune disease resulting in hair loss with devastating psychosocial consequences. Despite its high prevalence, there are no FDA-approved treatments for AA. Prior studies have identified a prominent interferon signature in AA, which signals through JAK molecules.A patient with AA was enrolled in a clinical trial to examine the efficacy of baricitinib, a JAK1/2 inhibitor, to treat concomitant CANDLE syndrome. In vivo, preclinical studies were conducted using the C3H/  ...[more]

Similar Datasets

2015-05-01 | E-GEOD-61554 | ArrayExpress
2015-05-01 | E-GEOD-61552 | ArrayExpress
2015-05-01 | E-GEOD-61551 | ArrayExpress
| PRJNA261449 | ENA
| PRJNA261448 | ENA
| PRJNA261447 | ENA
2014-08-17 | E-GEOD-45514 | ArrayExpress
| PRJNA112135 | ENA
| PRJNA194537 | ENA
2012-02-29 | GSE20715 | GEO