Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Colletotrichum falcatum strain:CoC 671

ABSTRACT: Colletotrichum falcatum strain:CoC 671 Transcriptome or Gene expression

PROVIDER: PRJNA272832 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Colletotrichum falcatum cultivar:CoC 671

Project description:Comparative transcriptome analysis of virulent and avirulent strains of Colletotrichum falcatum to unravel the pathogenic variations.

| PRJNA380334 | ENA

Colletotrichum falcatum strain:MAFF306170

Project description:Colletotrichum falcatum MAFF306170

| PRJNA262221 | ENA

Colletotrichum falcatum strain:MAFF306170

Project description:Colletotrichum falcatum MAFF306170

| PRJNA262215 | ENA

Colletotrichum falcatum strain:Cf08

Project description:Colletotrichum falcatum strain:Cf08 Genome sequencing and assembly

| PRJNA509540 | ENA

Colletotrichum falcatum strain:Cf671

Project description:Colletotrichum falcatum strain:Cf671 Genome sequencing and assembly

| PRJNA272959 | ENA

Colletotrichum falcatum cultivar:CoC 671 (Sugarcane cultivar variety)

Project description:Transcriptome analysis of sugarcane in response to Colletotrichum falcatum infection using RNA-Seq technology.

| PRJNA380333 | ENA

Analysis of differential proteins in Colletotrichum falcatum during red rot infection in sugarcane

Project description:The project is aimed at analysing the comparitive proteomics of red rot pathogen, C. falcatum, during red rot infection in sugarcane. The differentially abundant proteins shall be used to identify the corresponding genes.

2023-03-23 | PXD033368 | Pride

RNAseq Study in CC-671 Treated Cal-51 Cells

Project description:CC-671 has been identified as an inhibitor of Cdc2-like kinase 2 (CLK2) and TTK in direct enzyme assays. CLK2 is a member of the CLK family that phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex as part of a regulatory mechanism for control of pre-mRNA splicing. SR proteins are a family of small nuclear ribonucleoprotein particle (snRNP) splicing factors involved in constitutive and alternative splicing. Monitoring specific phospho-biomarkers of CLK2 demonstrated that CC-671 inhibited phosphorylation of CLK2 substrates in cancer cells with mean IC50 of 549 nM in the triple negative breast cancer (TNBC) line CAL51. In this study, RNA sequencing approach was used to quantify the impact of CC-671 treatment on gene transcription and global alternative splicing in CAL51 cells. Differential exon usage analysis demonstrated that CC-671 changed alternative splicing of many genes. In addition, different sets of genes are impacted by CC-671 at both the alternative splicing and mRNA expression. Genes impacted by alternative splicing shared a set of common pathways with genes altered by mRNA expression. This result indicates that CC-671 regulates transcription via both gene expression and alternative splicing mechanisms.

2018-04-23 | GSE113426 | GEO

miR-671-5p promotes epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer

Project description:microRNA (miRNA) dysfunction is associated with a variety of human diseases including cancer. Our previous study showed that miR-671-5p was deregulated during breast cancer progression. We aim to decipher the functional mechanism of miR- 671-5p in breast cancer. We used microarrays to detail the global programme of gene expression after overexpression miR-671-5p in several breast cancer cell lines, and those altered genes might potentially under regulation of miR-671-5p contibuting to breast cancer developemtn. miR-671-5p or scramble control nucleotide were tranfected into breast cancer cell lines, including MCF7, MDA231 and SKBR3. Total RNA were extracted and hybridized on Affymetrix microarrays. We sought to identify the potential downstream target genes that under miR-671-5p regulation by overexpress miR-671-5p. Potential targets were predicted to see if it has binding sites matching miR-671-5p sequence by miRNA target prediction softwares.

2014-10-16 | E-GEOD-62411 | biostudies-arrayexpress

Bupleurum falcatum

Project description:Bupleurum falcatum overview

| PRJNA413106 | ENA