Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Neonatal Skeletal Progenitors

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA273968 | ENA |

REPOSITORIES: ENA

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Publications


How are skeletal tissues derived from skeletal stem cells? Here, we map bone, cartilage, and stromal development from a population of highly pure, postnatal skeletal stem cells (mouse skeletal stem cells, mSSCs) to their downstream progenitors of bone, cartilage, and stromal tissue. We then investigated the transcriptome of the stem/progenitor cells for unique gene-expression patterns that would indicate potential regulators of mSSC lineage commitment. We demonstrate that mSSC niche factors can  ...[more]

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