Genomics

Dataset Information

0

Mus musculus


ABSTRACT: Genome-wide identification and analysis of microRNA expression in MEFs, ESCs, and iPSCs

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA274448 | ENA |

REPOSITORIES: ENA

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Publications

Establishment of leukemia inhibitory factor (LIF)-independent iPS cells with potentiated Oct4.

Hirai Hiroyuki H   Firpo Meri M   Kikyo Nobuaki N  

Stem cell research 20150912 3


Leukemia inhibitory factor (LIF) is widely used to establish and maintain naïve pluripotent stem cells, including mouse embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Although the combination of chemical inhibitors called 2i can establish mouse iPSCs without LIF from primed pluripotent stem cells, it has been difficult, if not impossible, to establish mouse iPSCs from differentiated somatic cells without LIF. We previously showed that the fusion gene of the transactivati  ...[more]

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