Dataset Information


Candida albicans

ABSTRACT: pH regulates white-opaque switching and sexual mating in Candida albicans

ORGANISM(S): Candida albicans  



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pH Regulates White-Opaque Switching and Sexual Mating in Candida albicans.

Sun Yuan Y   Cao Chengjun C   Jia Wei W   Tao Li L   Guan Guobo G   Huang Guanghua G  

Eukaryotic cell 20150904 11

As a successful commensal and pathogen of humans, Candida albicans encounters a wide range of environmental conditions. Among them, ambient pH, which changes frequently and affects many biological processes in this species, is an important factor, and the ability to adapt to pH changes is tightly linked with pathogenesis and morphogenesis. In this study, we report that pH has a profound effect on white-opaque switching and sexual mating in C. albicans. Acidic pH promotes white-to-opaque switchin  ...[more]

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