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Mycobacterium tuberculosis variant bovis BCG strain:Pasteur 1721

ABSTRACT: Mycobacterium tuberculosis variant bovis BCG strain:Pasteur 1721 Raw sequence reads

PROVIDER: PRJNA279402 | ENA |

REPOSITORIES: ENA

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Mycobacterium tuberculosis variant bovis BCG strain:Pasteur 1721

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Project description:Mycobacterial Ser/Thr kinases play a critical role in bacterial physiology and pathogenesis. Linking kinases to the substrates they phosphorylate in vivo, thereby elucidating their exact functions, is still a challenge. The aim of this work was to associate protein phosphorylation in mycobacteria with important subsequent macro cellular events by identifying the physiological substrates of PknG in Mycobacterium bovis BCG. The study compared the phosphoproteome dynamics during the batch growth of M. bovis BGC versus the respective PknG knock-out mutant (ΔPknG-BCG) strains.

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