Genomics

Dataset Information

118

Mus musculus


ABSTRACT: NeuroD2 ChIP-SEQ from embryonic cortex

ORGANISM(S): Mus musculus  

PROVIDER: PRJNA280213 | ENA |

REPOSITORIES: ENA

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Publications

Genome-wide target analysis of NEUROD2 provides new insights into regulation of cortical projection neuron migration and differentiation.

Bayam Efil E   Sahin Gulcan Semra GS   Guzelsoy Gizem G   Guner Gokhan G   Kabakcioglu Alkan A   Ince-Dunn Gulayse G  

BMC genomics 20150905


Cellular differentiation programs are controlled, to a large extent, by the combinatorial functioning of specific transcription factors. Cortical projection neurons constitute the major excitatory neuron population within the cortex and mediate long distance communication between the cortex and other brain regions. Our understanding of effector transcription factors and their downstream transcriptional programs that direct the differentiation process of cortical projection neurons is far from co  ...[more]

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