Caenorhabditis elegans
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA282401 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Expression data from L3 stage Caernorhabditis elegans after arsenic exposure
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Project description:We compared the pattern of H4K20me1 at the L3 stage in wild-type and set-4 mutants by ChIP-seq. In wild-type, H4K20me1 levels on the X chromosome are higher than on autosomes. In set-4 mutants, this difference is lost. ChIP-seq of H4K20me1 at the L3 stage in wild-type and set-4 mutant L3 larvae.
2012-08-01 | E-GEOD-39789 | biostudies-arrayexpress
Project description:We compared the pattern of H4K20me1 at the L3 stage in wild-type and set-4 mutants by ChIP-seq. In wild-type, H4K20me1 levels on the X chromosome are higher than on autosomes. In set-4 mutants, this difference is lost.
2012-08-01 | GSE39789 | GEO
Project description:Expression data from C. elegans during L3 and L3-lethargus
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Project description:High-throughput sequencing of mixed-stage Caenorhabditis elegans small RNAs. total RNA, ~18-26nt RNAs isolated using PAGE, ligation to adapters requires 5' monophosphate and 3' OH Keywords: high-throughput 454 sequencing
2006-10-15 | GSE5990 | GEO
Project description:To identify genes differentially expressed during L3 lethargus, we collected RNA during the third larval stage (L3) lethargus period, 37 hours after feeding developmentally-arrested L1 animals. Animals in lethargus were identified based on quiescence of locomotion and feeding. Additional time point for RNA collection was in the mid-L3 stage, 32 hours after feeding developmentally-arrested L1 animals. These samples were interrogated with the Affymetrix C. elegans Genome Array. A total of 153 gene transcripts were up regulated, and 48 gene transcripts were down regulated, during the L3 lethargus period compared to the L3 stage (false discovery rate (FDR) < 0.05).
2014-04-18 | GSE46288 | GEO
Project description:The goal of this study is to identify and characterize sites in the C. elegans genome bound by the transcription factor TRA-1. TRA-1 ChIP-seq was performed in the following stages of animals in duplicate: 1) L2 stage of C. elegans wild-type N2 strain; 2) L3 stage of C. elegans wild-type N2 strain; 3) young adult stage of C. elegans glp-4(bn2) mutant; 4) young adult stage of C. elegans spe-11(hc77) mutant; 5) L3 stage of C. briggsae wild-type AF16 strain. As a negative control, TRA-1 ChIP-seq was also performed in C. elegans L3 stage with tra-1(e1834) homozygous and heterozygous mutation. Input DNA was also sequenced in each condition.
2013-11-04 | E-GEOD-48917 | biostudies-arrayexpress
Project description:Small RNA in wild type Caenorhabditis elegans and ADAR mutants
| PRJNA288070 | ENA
Project description:We compare whole-animal RNA-seq transcriptomes for C. elegans males and hermaphrodites from the late L3 larval stage to young adulthood. During this interval, male sexual structures develop, including extensive neurogenesis and synaptogenesis that nearly doubles the size of the nervous system. Previous genome-wide expression studies in C. elegans have usually focused on only one sex â the hermaphrodite, and there are a relatively large number of predicted genes that still remain without meaningful annotation. In the present study, differential expression analysis of the RNA-seq data revealed 1,751 genes expressed at a higher level in the male. By differential expression analysis, unbiased gene correlation analysis, and a guilt-by-association approach, we identified new transcription factors required for differentiation of male genital structures, semen proteins, and candidates for previously-unknown components for synapse function. The results validate the dataset as a rich resource for future gene discovery in C. elegans. To analyze gene expression during sexual maturation in C. elegans, we performed RNA-seq for five samples for each sex ranging at 6 hr intervals from late L3 to young adult stages
2016-06-13 | E-GEOD-83216 | biostudies-arrayexpress
Project description:We compare whole-animal RNA-seq transcriptomes for C. elegans males and hermaphrodites from the late L3 larval stage to young adulthood. During this interval, male sexual structures develop, including extensive neurogenesis and synaptogenesis that nearly doubles the size of the nervous system. Previous genome-wide expression studies in C. elegans have usually focused on only one sex – the hermaphrodite, and there are a relatively large number of predicted genes that still remain without meaningful annotation. In the present study, differential expression analysis of the RNA-seq data revealed 1,751 genes expressed at a higher level in the male. By differential expression analysis, unbiased gene correlation analysis, and a guilt-by-association approach, we identified new transcription factors required for differentiation of male genital structures, semen proteins, and candidates for previously-unknown components for synapse function. The results validate the dataset as a rich resource for future gene discovery in C. elegans.
2016-06-13 | GSE83216 | GEO