Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

NextGen Consortium: The iPSCORE (iPSC Collection for Omic Research) Resource

ABSTRACT: NextGen Consortium: The iPSCORE (iPSC Collection for Omic Research) Resource

PROVIDER: PRJNA285374 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

NextGen Consortium: The iPSCORE (iPSC Collection for Omic Research) Resource - Whole Genome Sequence

Project description:NextGen Consortium: The iPSCORE (iPSC Collection for Omic Research) Resource - Whole Genome Sequence

| PRJNA378453 | ENA

NextGen Consortium: The iPSCORE (iPSC Collection for Omic Research) Resource

Project description:<p>The iPSCORE Resource of human induced pluripotent stem cells (hiPSCs) was created as part of the Next-Gen Consortium funded by the NHLBI. The overarching purpose of the iPSCORE Resource is to provide a large collection of hiPSCs for use in studying the impact of genetic variation on molecular and physiological phenotypes. This Resource is being used in a number of ongoing studies for which genomic data will be generated and deposited into public repositories and linked through dbGaP. A total of 273 individuals have participated in the study for which 222 have had hiPSCs generated from fibroblasts (available through WiCell (<a href="http://www.wicell.org/" target="_blank">http://www.wicell.org/</a>)). Of the 273 individuals, 181 are part of 55 families that include 24 monozygotic twin pairs and 5 dizygotic twin pairs, allowing for the incorporation of familial relationships into genetic analyses. Germline DNA has been sequenced from blood or fibroblast samples for all 273 individuals (see <a href="./study.cgi?study_id=phs001325">phs001325</a>) and other genomic data (RNA-seq, DNA methylation, and genotype arrays) has been generated from the 222 hiPSCs derived from a subset of these individuals (phs000924). Current studies include differentiation of these hiPSCs to other cell types, including cardiomyocytes and retinal pigment epithelium, and the generation of additional genomic data.</p>

| phs000924 | dbGaP

Project description:NextGen Consortium: The iPSCORE (iPSC Collection for Omic Research) Resource

| PRJNA521229 | ENA

Homo sapiens

Project description:NextGen Consortium: The iPSCORE (iPSC Collection for Omic Research) Resource

| PRJNA285375 | ENA

NextGen Consortium: The iPSCORE (iPSC Collection for Omic Research) Resource - Whole Genome Sequence

Project description:<p>The iPSCORE Resource of human induced pluripotent stem cells (hiPSCs) was created as part of the Next-Gen Consortium funded by the NHLBI. The overarching purpose of the iPSCORE Resource is to provide a large collection of hiPSCs for use in studying the impact of genetic variation on molecular and physiological phenotypes. This Resource is being used in a number of ongoing studies for which genomic data will be generated and deposited into public repositories and linked through dbGaP. A total of 273 individuals have participated in the study for which 222 have had hiPSCs generated from fibroblasts (available through WiCell (<a href="http://www.wicell.org/" target="_blank">http://www.wicell.org/</a>)). Of the 273 individuals, 181 are part of 55 families that include 24 monozygotic twin pairs and 5 dizygotic twin pairs, allowing for the incorporation of familial relationships into genetic analyses. Germline DNA has been sequenced from blood or fibroblast samples for all 273 individuals (this study) and other genomic data (RNA-seq, DNA methylation, and genotype arrays) has been generated from the 222 hiPSCs derived from a subset of these individuals (<a href="./study.cgi?study_id=phs000924">phs000924</a>). Current studies include differentiation of these hiPSCs to other cell types, including cardiomyocytes and retinal pigment epithelium, and the generation of additional genomic data.</p>

| phs001325 | dbGaP

Homo sapiens

Project description:NextGen Consortium: The iPSCORE (iPSC Collection for Omic Research) Resource - Whole Genome Sequence

| PRJNA378454 | ENA

Mutant Mouse Regional Resource Center (MMRRC) Research

Project description:This study is part of the Mutant Mouse Regional Resource Center Research. The series subsets represent the strain and age group for easy comparisons. Each subseries has data for three different tissues (brain, liver and kidney) and 2 sexes. Keywords: other

2005-10-18 | E-GEOD-1920 | biostudies-arrayexpress

Mutant Mouse Regional Resource Center (MMRRC) Research

2005-10-18 | GSE1920 | GEO

NextGen Goat WGS

Project description:NextGen Goat Whole Genome Sequencing data

| PRJEB5166 | ENA

Cloning and multi-omic analysis of chimpanzee cytomegalovirus: a resource for comparative functional genomics

Project description:Cloning and multi-omic analysis of chimpanzee cytomegalovirus: a resource for comparative functional genomics

| PRJNA718552 | ENA