Dataset Information


Homo sapiens

ABSTRACT: Vitamin D stimulation of primary skeletal muscle myoblasts

ORGANISM(S): Homo sapiens  



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Evidence for Vitamin D Receptor Expression and Direct Effects of 1α,25(OH)2D3 in Human Skeletal Muscle Precursor Cells.

Olsson Karl K   Saini Amarjit A   Strömberg Anna A   Alam Seher S   Lilja Mats M   Rullman Eric E   Gustafsson Thomas T  

Endocrinology 20151015 1

Presence of the vitamin D receptor and direct effects of vitamin D on the proliferation and differentiation of muscle precursor cells have been demonstrated in animal models. However, the effects and mechanisms of vitamin D actions in human skeletal muscle, and the presence of the vitamin D receptor in human adult skeletal muscle, remain to be established. Here, we investigated the role of vitamin D in human muscle cells at various stages of differentiation. We demonstrate that the components of  ...[more]

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