Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene Expression Profiling in Non-Human Primate Jejunum, Ileum and Colon after Total-Body Irradiation

ABSTRACT: Gene Expression Profiling in Non-Human Primate Jejunum, Ileum and Colon after Total-Body Irradiation

PROVIDER: PRJNA299016 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Gene Expression Profiling in Non-Human Primate Jejunum after Total-Body Irradiation

Project description:This is an experiment to study the effects of total body irradiation on intestinal gene expression. There are 24 male animals in the study; 4 controls, 10 animals received 6.7 Gy, 10 received 7.4 Gy. Animals were killed 4, 7 or 12 days after irradiation

2015-10-17 | GSE74107 | GEO

Gene Expression Profiling in Non-Human Primate Ileum after Total-Body Irradiation

2015-10-17 | GSE74109 | GEO

Gene expression profile of ileum, jejunum and colon

Project description:The gene expression of ileum, jejunum and colon.

2020-12-21 | GSE143342 | GEO

RNA-seq of mouse small intestinal epithelial cells sorted from duodenum, jejunum and ileum

Project description:Results of RNA-seq of normal C57BL/6 small intestinal epithelial cells sorted from duodenum, jejunum and ileum separately. Samples are named as follow; mouse replicate number-duodenum(1), jejunum(2) or ileum(3). For example, 1-1, 1-2 and 1-3 representing duodenum, jejunum and ileum respectively from mouse replicate number 1.

2021-01-21 | E-MTAB-9744 | biostudies-arrayexpress

Gene Expression Profiling in Non-Human Primate Jejunum, Ileum and Colon after Total-Body Irradiation

Project description:This SuperSeries is composed of the SubSeries listed below.

2015-10-17 | GSE74110 | GEO

Gene Expression Profiling in Non-Human Primate Colon after Total-Body Irradiation

2015-10-17 | GSE74108 | GEO

Region-specific identity of small intestinal stem cells from the ileum and jejunum

Project description:We report the expression profiles of three stem-cell varieties derived from the ileum and jejunum, focusing on gene signatures that are consistent in all stem cells of an intestinal location. We find that intestinal stem cells establish and maintain a regional identity that is discernable through gene expression patterns consistent with intestinal function particular to that region.

2015-07-01 | GSE53545 | GEO

Gene expression profile of ileum, jejunum and colon

Project description:Gene expression profile of ileum, jejunum and colon

| PRJNA600172 | ENA

Gene expression profiling in non-human primate jejunum, ileum and colon after total-body irradiation: a comparative study of segment-specific molecular and cellular responses.

Project description: Not available

| S-EPMC4654820 | biostudies-other

Project description:Rationale: Sepsis is a multi-organ disease affecting the ileum and jejunum (small intestine),liver, skeletal muscle, and lung clinically. Recently, specific alterations in circulating metabolites have been found in patients with sepsis which are thought to contribute to the pathogenesis of disease. The specific metabolic changes in the ileum, jejunum, liver, skeletal muscle, and lung have not previously been investigated. Methods: Live Pseudomonas aeruginosa isolated from a patient was given via IV catheter to pigs to induce severe sepsis. Eighteen hours later, ileum, jejunum, medial gastrocnemius skeletal muscle, liver, and lung were harvested and flash frozen. Tissues were subsequently processed for non-targeted metabolomics analysis using gas chromatography/mass spectrometry. Results: After 18 hours of sepsis, the ileum and the liver demonstrated significant changes in metabolites involved in linoleic acid metabolism, the ileum and lung had significant changes in valine/leucine/isoleucine metabolism, the jejunum, skeletal muscle, and liver had significant changes in arginine/ proline metabolism, and the skeletal muscle and lung had significant changes in aminoacyl-tRNA biosynthesis by pathway analysis. Pathway analysis also identified changes in metabolic pathways unique for different tissues, including changes in the citric acid cycle (jejunum), beta-alanine metabolism (skeletal muscle), and purine metabolism (liver). Conclusion: These findings demonstrate both overlapping metabolic pathways affected in different tissues and those that are unique to others and provide insight into the metabolic changes in sepsis leading to organ dysfunction. This may allow therapeutic interventions that focus on multiple tissues or single tissues once the relationship of the altered metabolites/metabolism to the underlying pathogenesis of sepsis is determined.

2018-12-03 | ST001190 | MetabolomicsWorkbench

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data