Project description:Gene-expression microarray datasets generated as part of the Immunological Genome Project (ImmGen) for samples that use a different set of amplification reagents (Ambion WT Expression Kit, not the Affymetrix GeneChip WT cDNA Synthesis and Amplification Kits).

2012-04-24 | GSE37448 | GEO

Eutherian interferons

Project description:Eutherian interferons

| PRJEB36709 | ENA

ImmGen ULI: Systemwide RNA-seq profiles (#1)

Project description:Primary RNAseq data for 127 highly purified immunocyte populations representing all lineages and several differentiation cascades, profiled using the ImmGen ULI pipeline.

2018-01-13 | GSE109125 | GEO

Influence of type I Interferons on function of splenic conventional dendritic cells.

Project description:Type I Interferons encompasses a large family of closely related cytokines comprising of at least 13 IFN-α isotypes and single IFN-β. Both IFN-α and IFN-β exert their activity through a common receptor IFNAR. Type I Interferons have broad regulatory effects and various subtypes of dendritic cells are influenced by this cytokines. In our study we asked question whether the low, constitutive levels of type I Interferons produced under steady state conditions are important for proper function of splenic conventional dendritic cells. In this approach we sorted out two populations (CD8α+ and CD8α-) of splenic dendritic cells (DCs) from untreated WT, IFN-β-/- and IFNAR-/- C57Bl/6 mice. All mice were between 8-10 weeks old. Further we isolated RNA and performed microarray analysis. Each DCs population was repeated twice.

2009-07-07 | E-GEOD-12392 | biostudies-arrayexpress

ImmGen ULI: Deep RNA-seq data

Project description:Primary RNAseq data for five highly purified immunocyte populations (splenic NK, Follicular B, Naïve CD4+ abT, gdT cells and peritoneal macrophages) profiled to unusual depth as multiple biological replicates, using the ImmGen ULI pipeline.

2018-11-16 | GSE122597 | GEO

Influence of type I Interferons on function of splenic conventional dendritic cells.

2009-07-07 | GSE12392 | GEO

ImmGen Microarray Phase 1

Project description:Gene-expression microarray datasets generated as part of the Immunological Genome Project (ImmGen). Primary cells from multiple immune lineages are isolated ex-vivo, primarily from young adult B6 male mice, and double-sorted to >99% purity. RNA is extracted from cells in a centralized manner, amplified and hybridized to Affymetrix 1.0 ST MuGene arrays. Protocols are rigorously standardized for all sorting and RNA preparation. Data is released monthly in batches of cell populations.

2009-05-02 | GSE15907 | GEO

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