Genomics

Dataset Information

0

Homo sapiens


ABSTRACT: Different gene expression signatures in children and adults with celiac disease

ORGANISM(S): Homo sapiens  

PROVIDER: PRJNA306513 | ENA |

REPOSITORIES: ENA

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Publications

Different Gene Expression Signatures in Children and Adults with Celiac Disease.

Pascual V V   Medrano L M LM   López-Palacios N N   Bodas A A   Dema B B   Fernández-Arquero M M   González-Pérez B B   Salazar I I   Núñez C C  

PloS one 20160209 2


Celiac disease (CD) is developed after gluten ingestion in genetically susceptible individuals. It can appear at any time in life, but some differences are commonly observed between individuals with onset early in life or in adulthood. We aimed to investigate the molecular basis underlying those differences. We collected 19 duodenal biopsies of children and adults with CD and compared the expression of 38 selected genes between each other and with the observed in 13 non-CD controls matched by ag  ...[more]

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